Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, The; A C Sterne, Jonathan; Murthy, Srinivas; Dı́az, Janet; S. Slutsky, Arthur; Villar, Jesús; C. Angus, Derek; Annane, Djillali; César Pontes Azevedo, Luciano; Berwanger, Otávio; Biasi Cavalcanti, Alexandre; Dequin, Pierre‐François; Du, Bin; Emberson, Jonathan; J. Fisher, David; Giraudeau, Bruno; Gordon, Anthony; Granholm, Anders; Green, Cameron; Haynes, Richard; Heming, Nicholas; P. T. Higgins, Julian; Horby, Peter; Jüni, Peter; Landray, Martin; Le Gouge, Amélie; Leclerc, M; Shen Lim, Wei; Machado, F.S.; McArthur, Colin; Meziani, Ferhat; Hylander Møller, Morten; Perner, Anders; Warrer Petersen, Marie; Savović, Jelena; Martins Tomazini, Bruno; Cordeiro Veiga, Viviane; Webb, Steve; C. Marshall, John

doi:10.1001/jama.2020.17023

Public

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

Published in JAMA • Sep 2, 2020

Authors:

The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group

Jonathan A C Sterne

Srinivas Murthy

Abstract

Importance: Effective therapies for patients with coronavirus disease 2019 (COVID-19) are needed, and clinical trial data have demonstrated that low-dose dexamethasone reduced mortality in hospitalized patients with COVID-19 who required respiratory support. Objective: To estimate the association be...

Subject

Medicine

Randomized controlled trial

Meta-analysis

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