Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

Abstract Innate lymphoid cells (ILCs) and CD4 + T cells produce IL-22, which is critical for intestinal immunity. The microbiota is central to IL-22 production in the intestines; however, the factors that regulate IL-22 production by CD4 + T cells and ILCs are not clear. Here, we show that microbiot... View More