Hypofractionated Versus Standard Fractionated Radiotherapy in Patients With Early Breast Cancer or Ductal Carcinoma In Situ in a Randomized Phase III Trial: The DBCG HYPO Trial

Vrou Offersen, Birgitte; Alsner, Jan; Melgaard Nielsen, Hanne; Jakobsen, Erik; Holck Nielsen, Mette; Krause, Mechthild; Stenbygaard, Lars; Mjaaland, Ingvil; Schreiber, Andreas; Kasti, Unn-Miriam; Overgaard, Jens

doi:10.1200/jco.20.01363

Public

Hypofractionated Versus Standard Fractionated Radiotherapy in Patients With Early Breast Cancer or Ductal Carcinoma In Situ in a Randomized Phase III Trial: The DBCG HYPO Trial

Published in Journal of Clinical Oncology • Sep 10, 2020

Authors:

Birgitte Vrou Offersen

Jan Alsner

Hanne Melgaard Nielsen

Abstract

PURPOSE: Given the poor results using hypofractionated radiotherapy for early breast cancer, a dose of 50 Gy in 25 fractions (fr) has been the standard regimen used by the Danish Breast Cancer Group (DBCG) since 1982. Results from more recent trials have stimulated a renewed interest in hypofraction...

Subject

Medicine

Ductal carcinoma

Radiation therapy

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