Sulforaphene Ameliorates Neuroinflammation and Hyperphosphorylated Tau Protein via Regulating the PI3K/Akt/GSK-3 β Pathway in Experimental Models of Alzheimer’s Disease

Yang, Wen; Liu, Yue; Xu, Qingqing; Xian, Yan‐Fang; Lin, Zhi‐Xiu

doi:10.1155/2020/4754195

Public

Sulforaphene Ameliorates Neuroinflammation and Hyperphosphorylated Tau Protein via Regulating the PI3K/Akt/GSK-3 β Pathway in Experimental Models of Alzheimer’s Disease

Published in Oxidative Medicine and Cellular Longevity • Sep 11, 2020

Authors:

Wen Yang

Yue Liu

Qingqing Xu

Abstract

Alzheimer’s disease (AD) is the most common form of dementia characterized by progressive loss of cognitive functions due to neuronal death mainly in the hippocampal and cortical brain. Sulforaphene (SF) is one of the main isothiocyanates isolated from a Chinese herb Raphani Semen. In this study, we...

Subject

Neuroinflammation

Neuroprotection

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