An outbreak of relapsing fever unmasked by microbial paleoserology, 16th century, France

Oumarou Hama, Hamadou; Barbieri, Rémi; Guirou, Jacqueline; Chenal, Thomas; Mayer, Aurélie; Ardagna, Yann; Signoli, Michel; Aboudharam, Gérard; Raoult, Didier; Drancourt, Michel

doi:10.1002/ajpa.24138

Public

An outbreak of relapsing fever unmasked by microbial paleoserology, 16th century, France

Published in American Journal of Physical Anthropology • Sep 21, 2020

Authors:

Hamadou Oumarou Hama

Rémi Barbieri

Jacqueline Guirou

Abstract

OBJECTIVES: Depicting past epidemics currently relies on DNA-based detection of pathogens, an approach limited to pathogens with well-preserved DNA sequences. We used paleoserology as a complementary approach detecting specific antibodies under a mini line-blot format including positive and negative...

Subject

Rickettsia prowazekii

Yersinia pestis

relapsing fever

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