SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum

Bruzzone, Chiara; Bizkarguenaga, Maider; Gil‐Redondo, Rubén; Diercks, Tammo; Arana‐Arri, Eunate; García de Vicuña, Aitor; Seco, Marisa; Bosch, Alexandre; Palazón, Asís; San Juan, Itxaso; Laín, Ana; Gil‐Martínez, Jon; Bernardo‐Seisdedos, Ganeko; Fernández‐Ramos, David; Lopitz‐Otsoa, Fernando; Embade, Nieves; C. Lu, Shelly; M. Mato, José; Millet, Óscar

doi:10.1016/j.isci.2020.101645

Public

SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum

Published in iScience • Oct 1, 2020

Authors:

Chiara Bruzzone

Maider Bizkarguenaga

Rubén Gil‐Redondo

Abstract

COVID-19 is a systemic infection that exerts significant impact on the metabolism. Yet, there is little information on how SARS-CoV-2 affects metabolism. Using NMR spectroscopy, we measured the metabolomic and lipidomic serum profile from 263 (training cohort) + 135 (validation cohort) symptomatic p...

Subject

Metabolomics

Oxidative stress

Dyslipidemia

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