Roles of IFN-γ in tumor progression and regression: a review

Jorgovanović, Dragica; Song, Mengjia; Wang, Liping; Zhang, Yi

doi:10.1186/s40364-020-00228-x

Public

Roles of IFN-γ in tumor progression and regression: a review

Published in Biomarker Research • Sep 29, 2020

Authors:

Dragica Jorgovanović

Mengjia Song

Liping Wang

Abstract

BACKGROUND: Interferon-γ (IFN-γ) plays a key role in activation of cellular immunity and subsequently, stimulation of antitumor immune-response. Based on its cytostatic, pro-apoptotic and antiproliferative functions, IFN-γ is considered potentially useful for adjuvant immunotherapy for different typ...

Subject

Tumor microenvironment

Downregulation and upregulation

Immunotherapy

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