Efficacy and Safety of Controlled Ovarian Stimulation With or Without Letrozole Co-administration for Fertility Preservation: A Systematic Review and Meta-Analysis.

B, Bonardi; C, Massarotti; M, Bruzzone; O, Goldrat; G, Mangili; P, Anserini; S, Spinaci; L, Arecco; Mastro L, Del; M, Ceppi; I, Demeestere; M, Lambertini

doi:10.3389/fonc.2020.574669

Public

Efficacy and Safety of Controlled Ovarian Stimulation With or Without Letrozole Co-administration for Fertility Preservation: A Systematic Review and Meta-Analysis.

Shared by NobleBlocks on Oct 7, 2020 • 12:00 AM UTC

Authors:

Bonardi B

Massarotti C

Bruzzone M

Abstract

Background: The co-administration of letrozole during controlled ovarian stimulation (COS) with gonadotropins is used to limit the potentially harmful effects of a supra-physiological rise in estrogen levels on hormone-sensitive cancers. However, the efficacy and safety of adding letrozole to COS re...

Subject

Fertility

Breast cancer

Gonadotropins

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