Pembrolizumab with or without radiation therapy for metastatic non-small cell lung cancer: a randomized phase I/II trial

W. Welsh, James; Menon, Hari; Chen, Dawei; Verma, Vivek; Tang, Chad; Altan, Mehmet; R. Hess, Kenneth; M. de Groot, Patricia; Nguyen, Quynh‐Nhu; Varghese, Rejani; Comeaux, Nathan; R. Simon, George; Skoulidis, Ferdinandos; Y. Chang, Joe; Papdimitrakopoulou, Vasiliki; H. Lin, Steven; V. Heymach, John

doi:10.1136/jitc-2020-001001

Public

Pembrolizumab with or without radiation therapy for metastatic non-small cell lung cancer: a randomized phase I/II trial

Published in Journal for ImmunoTherapy of Cancer • Oct 1, 2020

Authors:

James W. Welsh

Hari Menon

Dawei Chen

Abstract

BACKGROUND: In this phase I/II trial, we evaluated the safety and effectiveness of pembrolizumab, with or without concurrent radiotherapy (RT), for lung and liver lesions from metastatic non-small cell lung cancer (mNSCLC). METHODS: Patients with lung or liver lesions amenable to RT plus at least on...

Subject

Pembrolizumab

Medicine

Lung cancer

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