Proteomic Evaluation of the Comorbidity-Inflammation Paradigm in Heart Failure With Preserved Ejection Fraction

Sanders‐van Wijk, Sandra; Tromp, Jasper; Beussink‐Nelson, Lauren; Hage, Camilla; Svedlund, Sara; Saraste, Antti; Swat, Stanley; Sanchez, Cynthia; Njoroge, Joyce; Tan, Ru‐San; Lagerström‐Fermér, Maria; Gan, Li‐Ming; H. Lund, Lars; S.P. Lam, Carolyn; J. Shah, Sanjiv

doi:10.1161/circulationaha.120.045810

Public

Proteomic Evaluation of the Comorbidity-Inflammation Paradigm in Heart Failure With Preserved Ejection Fraction

Published in Circulation • Oct 9, 2020

Authors:

Sandra Sanders‐van Wijk

Jasper Tromp

Lauren Beussink‐Nelson

Abstract

Background: A systemic proinflammatory state has been hypothesized to mediate the association between comorbidities and abnormal cardiac structure/function in heart failure with preserved ejection fraction (HFpEF). We conducted a proteomic analysis to investigate this paradigm. Methods: In 228 patie...

Subject

Medicine

Comorbidity

Heart failure

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