Association of SGLT2 Inhibitors With Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes

K. McGuire, Darren; Shih, Weichung; Cosentino, Francesco; Charbonnel, B; Z.I. Cherney, David; Dagogo‐Jack, Samuel; E. Pratley, Richard; Greenberg, Michelle; Wang, Shuai; Huyck, Susan; Gantz, Ira; G. Terra, Steven; Masiukiewicz, Urszula; P. Cannon, Christopher

doi:10.1001/jamacardio.2020.4511

Public

Association of SGLT2 Inhibitors With Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes

Published in JAMA Cardiology • Oct 7, 2020

Authors:

Darren K. McGuire

Weichung Shih

Francesco Cosentino

Abstract

Importance: Sodium-glucose cotransporter 2 (SGLT2) inhibitors favorably affect cardiovascular (CV) and kidney outcomes; however, the consistency of outcomes across the class remains uncertain. Objective: To perform meta-analyses that assess the CV and kidney outcomes of all 4 available SGLT2 inhibit...

Subject

Medicine

Type 2 diabetes

Hazard ratio

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