Efficacy of Dapagliflozin on Renal Function and Outcomes in Patients With Heart Failure With Reduced Ejection Fraction

S. Jhund, Pardeep; D. Solomon, Scott; F. Docherty, Kieran; J.L. Heerspink, Hiddo; S. Anand, Inder; Böhm, Michael; Chopra, Vijay; A. de Boer, Rudolf; S. Desai, Akshay; Ge, Junbo; Kitakaze, Masafumi; Merkley, Bela; O'Meara, Eileen; Shou, Morten; Tereshchenko, Sergey; Verma, Subodh; Nguyen Vinh, Pham; E. Inzucchi, Silvio; Køber, Lars; N. Kosiborod, Mikhail; A. Martinez, Felipe; Ponikowski, Piotr; S. Sabatine, Marc; Bengtsson, Olof; Maria Langkilde, Anna; Sjöstrand, Mikaela; J.V. McMurray, John

doi:10.1161/circulationaha.120.050391

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Efficacy of Dapagliflozin on Renal Function and Outcomes in Patients With Heart Failure With Reduced Ejection Fraction

Shared by NobleBlocks on Jan 26, 2021 • 12:00 AM UTC

Authors:

Pardeep S. Jhund

Scott D. Solomon

Kieran F. Docherty

Abstract

Background: Many patients with heart failure and reduced ejection fraction (HFrEF) have chronic kidney disease that complicates pharmacological management and is associated with worse outcomes. We assessed the safety and efficacy of dapagliflozin in patients with HFrEF, according to baseline kidney ...

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