Elevated Exhaustion Levels of NK and CD8+ T Cells as Indicators for Progression and Prognosis of COVID-19 Disease

Li, Mingyue; Guo, Weina; Dong, Yalan; Wang, Xiaobei; Dai, Die; Liu, Xingxing; Wu, Yiquan; Li, Mengmeng; Zhang, Wenjing; Zhou, Haifeng; Zhang, Zili; Lin, Lan; Kang, Zhenyu; Yu, Ting; Tian, Chunxia; Qin, Renjie; Yang, Gui; Jiang, Feng; Fan, Heng; Heissmeyer, Vigo; Sarapultsev, Alexey; Wang, Lin; Luo, Shanshan; Hu, Desheng

doi:10.3389/fimmu.2020.580237

Public

Elevated Exhaustion Levels of NK and CD8+ T Cells as Indicators for Progression and Prognosis of COVID-19 Disease

Published in Frontiers in Immunology • Oct 14, 2020

Authors:

Mingyue Li

Weina Guo

Yalan Dong

Abstract

Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) induced Coronavirus Disease 2019 (COVID-19) has posed a global threat to public health. The immune system is crucial in defending and eliminating the virus and infected cells. However, immune dysregulation may result in the rap...

Subject

Coronavirus disease 2019 (COVID-19)

Disease

Immunology

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