The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study

Pei, Yu‐Fang; Liu, Yaozhong; Yang, Xiaolin; Zhang, Hong; Feng, Guijuan; Wei, Xin‐Tong; Zhang, Lei

doi:10.1038/s42003-020-01334-0

Public

The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study

Published in Communications Biology • Oct 23, 2020

Authors:

Yu‐Fang Pei

Yaozhong Liu

Xiaolin Yang

Abstract

Abstract Appendicular lean mass (ALM) is a heritable trait associated with loss of lean muscle mass and strength, or sarcopenia, but its genetic determinants are largely unknown. Here we conducted a genome-wide association study (GWAS) with 450,243 UK Biobank participants to uncover its genetic arch...

Subject

Genome-wide association study

Heritability

Biobank

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