A Heart‐Breast Cancer‐on‐a‐Chip Platform for Disease Modeling and Monitoring of Cardiotoxicity Induced by Cancer Chemotherapy

Lee, Junmin; Mehrotra, Shreya; Zare‐Eelanjegh, Elaheh; O. Rodrigues, Raquel; Akbarinejad, Alireza; H. Ge, David; Amato, L.; Kiaee, Kiavash; Fang, Yongcong; Rosenkranz, Aliza; Keung, Wendy; B. Mandal, Biman; A. Li, Ronald; Zhang, Ting; Lee, HeaYeon; R. Dokmeci, Mehmet; Shrike Zhang, Yu; Khademhosseini, Ali; Ryon Shin, Su

doi:10.1002/smll.202004258

Public

A Heart‐Breast Cancer‐on‐a‐Chip Platform for Disease Modeling and Monitoring of Cardiotoxicity Induced by Cancer Chemotherapy

Published in Small • Oct 23, 2020

Authors:

Junmin Lee

Shreya Mehrotra

Elaheh Zare‐Eelanjegh

Abstract

Cardiotoxicity is one of the most serious side effects of cancer chemotherapy. Current approaches to monitoring of chemotherapy-induced cardiotoxicity (CIC) as well as model systems that develop in vivo or in vitro CIC platforms fail to notice early signs of CIC. Moreover, breast cancer (BC) patient...

Subject

Cardiotoxicity

Breast cancer

Medicine

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