Antiviral Peptides as Promising Therapeutics against SARS-CoV-2

Mohammad Chowdhury, Surid; Ahmad Talukder, Shafi; Mahmud Khan, Akib; Afrin, Nadia; Ali, Muhammad; Islam, Rajib; Rimon Parves, Md.; Al Mamun, Abdulla; Abu Sufian, Md; Nayeem Hossain, Md; Akhter Hossain, Mohammed; A. Halim, Mohammad

doi:10.1021/acs.jpcb.0c05621

Public

Antiviral Peptides as Promising Therapeutics against SARS-CoV-2

Published in The Journal of Physical Chemistry B • Oct 23, 2020

Authors:

Surid Mohammad Chowdhury

Shafi Ahmad Talukder

Akib Mahmud Khan

Abstract

Over 50 peptides, which were known to inhibit SARS-CoV-1, were computationally screened against the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2. Based on the binding affinity and interaction, 15 peptides were selected, which showed higher affinity compared to the α-helix of the ...

Subject

Peptide

Chemistry

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

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