Long-term outcome and prognostic value of Ki67 after perioperative endocrine therapy in postmenopausal women with hormone-sensitive early breast cancer (POETIC): an open-label, multicentre, parallel-group, randomised, phase 3 trial

Smith, Ian; Robertson, J.F.R.; Kilburn, Lucy; Wilcox, Maggie; Evans, Abigail; Holcombe, Chris; Horgan, Kieran; Kirwan, Cliona; Mallon, Elizabeth; Sibbering, Mark; Skene, Anthony; Vidya, Raghavan; C.U. Cheang, Maggie; Banerji, Jane; P. Morden, James; Sidhu, Kally; Dodson, Andrew; M. Bliss, Judith; Dowsett, Mitch

doi:10.1016/s1470-2045(20)30458-7

Public

Long-term outcome and prognostic value of Ki67 after perioperative endocrine therapy in postmenopausal women with hormone-sensitive early breast cancer (POETIC): an open-label, multicentre, parallel-group, randomised, phase 3 trial

Published in The Lancet Oncology • Nov 1, 2020

Authors:

Ian Smith

J.F.R. Robertson

Lucy Kilburn

Abstract

BACKGROUND: ). The POETIC trial aimed to test these two hypotheses. METHODS: POETIC was an open-label, multicentre, parallel-group, randomised, phase 3 trial (done in 130 UK hospitals) in which postmenopausal women aged at least 50 years with WHO performance status 0-1 and hormone receptor-positive,...

Subject

Medicine

Clinical endpoint

Letrozole

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