Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

Weisblum, Yiska; Schmidt, Fabian; Zhang, Fengwen; DaSilva, Justin; Poston, Daniel; CC Lorenzi, Júlio; Muecksch, Frauke; Rutkowska, Magdalena; Hoffmann, Hans-Heinrich; Michailidis, Eleftherios; Gaebler, Christian; Agudelo, Marianna; Cho, Alice; Wang, Zijun; Gazumyan, Anna; Cipolla, Melissa; L. Luchsinger, Larry; D. Hillyer, Christopher; Caskey, Marina; F. Robbiani, Davide; M. Rice, Charles; C. Nussenzweig, Michel; Hatziioannou, Théodora; D. Bieniasz, Paul

doi:10.7554/elife.61312

Public

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

Published in eLife • Oct 28, 2020

Authors:

Yiska Weisblum

Fabian Schmidt

Fengwen Zhang

Abstract

Neutralizing antibodies elicited by prior infection or vaccination are likely to be key for future protection of individuals and populations against SARS-CoV-2. Moreover, passively administered antibodies are among the most promising therapeutic and prophylactic anti-SARS-CoV-2 agents. However, the ...

Subject

Spike Protein

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Virology

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