Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections

Feng, Liwen; Pomel, Sébastien; Latré de Laté, Perle; Taravaud, Alexandre; M. Loiseau, Philippe; Maes, Louis; Cho‐Ngwa, Fidelis; A. Bulman, Christina; Fischer, Chelsea; A. Sakanari, Judy; Ziniel, Peter; L. Williams, David; Davioud–Charvet, Elisabeth

doi:10.3390/molecules25215075

Public

Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections

Published in Molecules • Nov 1, 2020

Authors:

Liwen Feng

Sébastien Pomel

Perle Latré de Laté

Abstract

Neglected parasitic diseases remain a major public health issue worldwide, especially in tropical and subtropical areas. Human parasite diversity is very large, ranging from protozoa to worms. In most cases, more effective and new drugs are urgently needed. Previous studies indicated that the gold(I...

Subject

Auranofin

Thioredoxin reductase

Biology

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