Changes in SARS-CoV-2 Spike versus Nucleoprotein Antibody Responses Impact the Estimates of Infections in Population-Based Seroprevalence Studies

Fenwick, Craig; Croxatto, Antony; T. Coste, Alix; Pojer, Florence; André, Cyril; Pellaton, Céline; Farina, Alex; Campos, Jérémy; L. Hacker, David; Lau, Kelvin; Bosch, Berend‐Jan; Gonseth, Semira; Bochud, Murielle; D’Acremont, Valérie; Trono, Didier; Greub, Gilbert; Pantaleo, Giuseppe

doi:10.1128/jvi.01828-20

Public

Changes in SARS-CoV-2 Spike versus Nucleoprotein Antibody Responses Impact the Estimates of Infections in Population-Based Seroprevalence Studies

Published in Journal of Virology • Nov 3, 2020

Authors:

Craig Fenwick

Antony Croxatto

Alix T. Coste

Abstract

In the present study, we have determined SARS-CoV-2-specific antibody responses in sera of acute and postinfection phase subjects. Our results indicate that antibody responses against viral S and N proteins were equally sensitive in the acute phase of infection, but that responses against N appear t...

Subject

Seroprevalence

Antibody

Biology

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