A Probiotic <i>Lactobacillus gasseri</i> Alleviates <i>Escherichia coli</i>-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1β Expression and Gut Microbiota.

SW, Yun; JK, Kim; KE, Lee; YJ, Oh; HJ, Choi; MJ, Han; DH, Kim

doi:10.3390/nu12113441

Public

A Probiotic Lactobacillus gasseri Alleviates Escherichia coli-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1β Expression and Gut Microbiota.

Shared by NobleBlocks on Nov 10, 2020 • 12:00 AM UTC

Authors:

Yun SW

Kim JK

Lee KE

Abstract

Excessive expression of interleukin (IL)-1β in the brain causes depression and cognitive dysfunction. Herein, we investigated the effect of Lactobacillus gasseri NK109, which suppressed IL-1β expression in activated macrophages, on Escherichia coli K1-induced cognitive impairment and depression in m...

Subject

IL-1β

Depression

Gut Microbiota

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