A Probiotic Lactobacillus gasseri Alleviates Escherichia coli-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1β Expression and Gut Microbiota

Yun, Soo-Won; Kim, Jeon-Kyung; Lee, Kyung‐Eon; J. Oh, Young; Choi, Hak‐Jong; Joo Han, Myung; Kim, Dong‐Hyun

doi:10.3390/nu12113441

Public

A Probiotic Lactobacillus gasseri Alleviates Escherichia coli-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1β Expression and Gut Microbiota

Published in Nutrients • Nov 10, 2020

Authors:

Soo-Won Yun

Jeon-Kyung Kim

Kyung‐Eon Lee

Abstract

Excessive expression of interleukin (IL)-1β in the brain causes depression and cognitive dysfunction. Herein, we investigated the effect of Lactobacillus gasseri NK109, which suppressed IL-1β expression in activated macrophages, on Escherichia coli K1-induced cognitive impairment and depression in m...

Subject

Lactobacillus gasseri

Lactobacillus reuteri

Gut–brain axis

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