Intussusception after Rotavirus Vaccine Introduction in India

Reddy N, Samarasimha; P. Nair, Nayana; E. Tate, Jacqueline; Thiyagarajan, Varunkumar; Giri, Sidhartha; Praharaj, Ira; Raghava Mohan, Venkata; Babji, Sudhir; D Gupte, M; Arora, Rashmi; Bidari, Sunita; Senthamizh, Sowmiya; Mekala, Suhasini; Babu Goru, Krishna; Reddy, Bhaskar; Pamu, Padmalatha; P. Gorthi, Rajendra; Badur, Manohar; Mohan, Vittal; Sathpathy, Saroj; Kishor Mohanty, Hiranya; Dash, Mrutunjay; Kumar Mohakud, Nirmal; Kumar Ray, Rajib; Mohanty, Prasantajyoti; Gathwala, Geeta; Chawla, Suraj; Gupta, Madhu; Gupta, Rajkumar; Goyal, Suresh; Sharma, Pramod; Abraham Mathew, Mannancheril; John K Jacob, Tarun; Balasubramanian, Sundaram; K.C. Purushothaman, Girish; Dorairaj, Priyadarishini; Jagannatham, Muthukumaran; Murugiah, Kulandaivel; Boopathy, Hemanthkumar; Maniam, Raghul; Gurusamy, Rajamani; Kumaravel, Sambandan; Shenoy, Ashwitha; Jain, Hemant; Kumar Goswami, Jayanta; Wakhlu, Ashish; Gupta, Vineeta; Vinayagamurthy, Gopinath; D. Parashar, Umesh; Kang, Gagandeep

doi:10.1056/nejmoa2002276

Public

Intussusception after Rotavirus Vaccine Introduction in India

Published in New England Journal of Medicine • Nov 11, 2020

Authors:

Samarasimha Reddy N

Nayana P. Nair

Jacqueline E. Tate

Abstract

BACKGROUND: A three-dose, oral rotavirus vaccine (Rotavac) was introduced in the universal immunization program in India in 2016. A prelicensure trial involving 6799 infants was not large enough to detect a small increased risk of intussusception. Postmarketing surveillance data would be useful in a...

Subject

Rotavirus vaccine

Intussusception (medical disorder)

Rotavirus

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