Metabolites of microbiota response to tryptophan and intestinal mucosal immunity: A therapeutic target to control intestinal inflammation

Zhang, Jie; Zhu, Shengwei; Ma, Ning; J. Johnston, L.; Wu, Chaodong; Ma, Xi

doi:10.1002/med.21752

Public

Metabolites of microbiota response to tryptophan and intestinal mucosal immunity: A therapeutic target to control intestinal inflammation

Published in Medicinal Research Reviews • Nov 10, 2020

Authors:

Jie Zhang

Shengwei Zhu

Ning Ma

Abstract

In a complex, diverse intestinal environment, commensal microbiota metabolizes excessive dietary tryptophan to produce more bioactive metabolites connecting with kinds of diverse process, such as host physiological defense, homeostasis, excessive immune activation and the progression and outcome of ...

Subject

Biology

Intestinal mucosa

Immune system

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