Radiomics to predict outcomes and abscopal response of patients with cancer treated with immunotherapy combined with radiotherapy using a validated signature of CD8 cells

Sun, Roger; Sundahl, Nora; Hecht, Markus; Putz, Florian; Lancia, Andrea; Rouyar, Angéla; Milić, Marina; Carré, Alexandre; Battistella, Enzo; Alvarez Andres, Émilie; Niyoteka, Stéphane; Romano, Edouard; Louvel, G.; Durand-Labrunie, Jérôme; Bockel, Sophie; Bahleda, Rastilav; Robert, Charlotte; Boutros, C.; Vakalopoulou, Maria; Paragios, Nikos; Frey, Benjamin; Soria, Jean‐Charles; Massard, Christophe; Ferté, Charles; Fietkau, Rainer; Ost, Piet; S. Gaipl, Udo; Deutsch, Éric

doi:10.1136/jitc-2020-001429

Public

Radiomics to predict outcomes and abscopal response of patients with cancer treated with immunotherapy combined with radiotherapy using a validated signature of CD8 cells

Published in Journal for ImmunoTherapy of Cancer • Nov 1, 2020

Authors:

Roger Sun

Nora Sundahl

Markus Hecht

Abstract

BACKGROUND: Combining radiotherapy (RT) with immuno-oncology (IO) therapy (IORT) may enhance IO-induced antitumor response. Quantitative imaging biomarkers can be used to provide prognosis, predict tumor response in a non-invasive fashion and improve patient selection for IORT. A biologically inspir...

Subject

Medicine

Radiomics

Lesion

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