TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment

Sun, Dongqing; Wang, Jin; Han, Ya; Dong, Xin; Ge, Jun; Zheng, Rongbin; Shi, Xiaoying; Wang, Binbin; Li, Ziyi; Ren, Pengfei; Sun, Liangdong; Yan, Yilv; Zhang, Peng; Zhang, Fan; Li, Taiwen; Wang, Chenfei

doi:10.1093/nar/gkaa1020

Public

TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment

Published in Nucleic Acids Research • Oct 16, 2020

Authors:

Dongqing Sun

Jin Wang

Ya Han

Abstract

Cancer immunotherapy targeting co-inhibitory pathways by checkpoint blockade shows remarkable efficacy in a variety of cancer types. However, only a minority of patients respond to treatment due to the stochastic heterogeneity of tumor microenvironment (TME). Recent advances in single-cell RNA-seq t...

Subject

Biology

Transcriptome

Visualization

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