Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure

Xavier López‐Labrador, F.; R. Brown, Julianne; Fischer, Nicole; Harvala, Heli; van Boheemen, Sander; Cinek, Ondřej; Sayıner, Arzu; Vasehus Madsen, Tina; Auvinen, Eeva; Kufner, Verena; Huber, Michael; Rodriguez, Christophe; Jonges, Marcel; Hönemann, Mario; Susi, Petri; Sousa, Hugo; E. Klapper, Paul; Pérez‐Cataluña, Alba; Hernández, Marta; Molenkamp, Richard; van der Hoek, Lia; Schuurman, Rob; Couto, Natacha; Leuzinger, Karoline; Simmonds, Peter; Beer, Martin; W. Höper, Dirk; Kamminga, Sergio; C.W. Feltkamp, Mariet; Rodríguez‐Díaz, Jesús; Keyaerts, Els; Chen Nielsen, Xiaohui; Puchhammer‐Stöckl, Elisabeth; C.M. Kroes, Aloys; Buesa, Javier; Breuer, Judy; C. J. Claas, Eric; J.C. de Vries, Jutte

doi:10.1016/j.jcv.2020.104691

Public

Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure

Published in Journal of Clinical Virology • Nov 18, 2020

Authors:

F. Xavier López‐Labrador

Julianne R. Brown

Nicole Fischer

Abstract

Metagenomic high-throughput sequencing (mHTS) is a hypothesis-free, universal pathogen detection technique for determination of the DNA/RNA sequences in a variety of sample types and infectious syndromes. mHTS is still in its early stages of translating into clinical application. To support the deve...

Subject

Metagenomics

Standardization

DNA sequencing

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