Etiology of Severe Community-Acquired Pneumonia in Adults Based on Metagenomic Next-Generation Sequencing: A Prospective Multicenter Study

Wu, Xiaodong; Li, Yuanyuan; Zhang, Ming; Li, Miaomiao; Zhang, Rong; Lü, Xin; Gao, Wei; Li, Qin; Li, Qin; Xia, Yang; Pan, Pinhua; Li, Qiang; Li, Qiang

doi:10.1007/s40121-020-00353-y

Public

Etiology of Severe Community-Acquired Pneumonia in Adults Based on Metagenomic Next-Generation Sequencing: A Prospective Multicenter Study

Published in Infectious Diseases and Therapy • Nov 10, 2020

Authors:

Xiaodong Wu

Yuanyuan Li

Ming Zhang

Abstract

BACKGROUND: Metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid (BALF) has the potential to improve the pathogen identification in severe community-acquired pneumonia (SCAP). METHODS: In this 1.5-year, multicenter, prospective study, we investigated the usefulness of mNGS o...

Subject

Streptococcus pneumoniae

Medicine

Haemophilus influenzae

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