Cu(ii) and V(iv)O complexes with tri- or tetradentate ligands based on (2-hydroxybenzyl)-l-alanines reveal promising anticancer therapeutic potential.

N, Ribeiro; I, Bulut; B, Cevatemre; C, Teixeira; Y, Yildizhan; V, André; P, Adão; JC, Pessoa; C, Acilan; I, Correia

doi:10.1039/d0dt03331f

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Cu(ii) and V(iv)O complexes with tri- or tetradentate ligands based on (2-hydroxybenzyl)-l-alanines reveal promising anticancer therapeutic potential.

Shared by NobleBlocks on Dec 8, 2020 • 12:00 AM UTC

Authors:

Ribeiro N

Bulut I

Cevatemre B

Abstract

Four new ligand precursors (H2L1-H2L4), derived from the Mannich condensation of two amino acids (l-Val and l-Phe) and two 3,5-disubstituted phenols (t-Bu or Me), and the corresponding oxidovanadium(iv) (1-4) and copper(ii) (6-7) complexes are synthesized. Two other related compounds (H2L5 and H2L6)...

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