CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

Wang, Ke; Chen, Wei; Zhang, Zheng; Deng, Yong‐Qiang; Lian, Jianqi; Du, Peng; Ding, Wei; Yang, Zhang; Sun, Xiuxuan; Gong, Li; Yang, Xu; He, Lei; Zhang, Lei; Yang, Zhiwei; Geng, Jiejie; Chen, Ruo; Zhang, Hai; Wang, Bin; Zhu, Yumeng; Nan, Gang; Jiang, Jian‐Li; Li, Ling; Wu, Jiao; Lin, Peng; Huang, Wan; Xie, Liangzhi; Zheng, Zhaohui; Zhang, Kui; Miao, Jinlin; Cui, Hong‐Yong; Huang, Min; Zhang, Jun; Fu, Ling; Yang, Xiang-Min; Zhao, Zhongpeng; Sun, Shihui; Gu, Hongjing; Wang, Zhe; Wang, Chunfu; Lu, Ya-Cheng; Liu, Yingying; Wang, Qingyi; Bian, Huijie; Zhu, Ping; Chen, Zhi‐Nan

doi:10.1038/s41392-020-00426-x

Public

CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

Published in Signal Transduction and Targeted Therapy • Dec 4, 2020

Authors:

Ke Wang

Wei Chen

Zheng Zhang

Abstract

In face of the everlasting battle toward COVID-19 and the rapid evolution of SARS-CoV-2, no specific and effective drugs for treating this disease have been reported until today. Angiotensin-converting enzyme 2 (ACE2), a receptor of SARS-CoV-2, mediates the virus infection by binding to spike protei...

Subject

Vero cell

Virus

Virology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!