CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

Wang, Ke; Chen, Wei; Zhang, Zheng; Deng, Yongqiang; Lian, Jian-Qi; Du, Peng; Wei, Ding; Zhang, Yang; Sun, Xiu-Xuan; Gong, Li; Yang, Xu; He, Lei; Zhang, Lei; Yang, Zhiwei; Geng, Jie-Jie; Chen, Ruo; Zhang, Hai; Wang, Bin; Zhu, Yu-Meng; Nan, Gang; Jiang, Jian-Li; Li, Ling; Wu, Jiao; Lin, Peng; Huang, Wan; Xie, Liangzhi; Zheng, Zhao-Hui; Zhang, Kui; Miao, Jin-Lin; Cui, Hong-Yong; Huang, Min; Zhang, Jun; Fu, Ling; Yang, Xiang-Min; Zhao, Zhongpeng; Sun, Shihui; Gu, Hongjing; Wang, Zhe; Wang, Chun-Fu; Lu, Yacheng; Liu, Ying-Ying; Wang, Qing-Yi; Bian, Huijie; Zhu, Ping; Chen, Zhi-Nan

doi:10.1038/s41392-020-00426-x

Public

CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

Shared by NobleBlocks on Dec 4, 2020 • 12:00 AM UTC

Authors:

Ke Wang

Wei Chen

Zheng Zhang

Abstract

Abstract In face of the everlasting battle toward COVID-19 and the rapid evolution of SARS-CoV-2, no specific and effective drugs for treating this disease have been reported until today. Angiotensin-converting enzyme 2 (ACE2), a receptor of SARS-CoV-2, mediates the virus infection by binding to spi...

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