Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1α-NF-κB Crosstalk In Vitro and In Vivo

Ngullie Chang, Sukkum; Kumar Dey, Debasish; Taek Oh, Seong; Ho Kong, Won; Hyung Cho, Kiu; Al‐Olayan, Ebtesam; Su Hwang, Buyng; Chul Kang, Sun; Gyu Park, Jae

doi:10.3390/ijms21239261

Public

Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1α-NF-κB Crosstalk In Vitro and In Vivo

Published in International Journal of Molecular Sciences • Dec 4, 2020

Authors:

Sukkum Ngullie Chang

Debasish Kumar Dey

Seong Taek Oh

Abstract

root tip and induced mitotic dysfunction. Similarly, PMA caused embryonic and larval deformities and a plummeted survivability rate on zebrafish embryo in a dose-dependent manner. Persistently, PMA treatment on immortalized human keratinocyte human keratinocyte (HaCaT) cells caused massive inflammat...

Subject

HaCaT

Keratinocyte

In vivo

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