Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR

K. Smith, Alicia; Ratanatharathorn, Andrew; X. Maihofer, Adam; K. Naviaux, Robert; E. Aiello, Allison; B. Amstadter, Ananda; E. Ashley‐Koch, Allison; G. Baker, Dewleen; C. Beckham, Jean; P. Boks, Marco; J. Bromet, Evelyn; F. Dennis, Michelle; Galea, Sandro; E. Garrett, Melanie; Geuze, Elbert; Guffanti, Guia; A. Hauser, Michael; Katrinli, Şeyma; Kilaru, Varun; C. Kessler, Ronald; A. Kimbrel, Nathan; C. Koenen, Karestan; Fen Kuan, Pei; Li, Kefeng; W. Logue, Mark; Lori, Adriana; J. Luft, Benjamin; W. Miller, Mark; C. Naviaux, Jane; R Nugent, Nicole; Qin, Xuejun; J. Ressler, Kerry; B. Risbrough, Victoria; P. F. Rutten, Bart; B. Stein, Murray; J. Ursano, Robert; Vermetten, Eric; H. Vinkers, Christiaan; Wang, Lin; A. Youssef, Nagy; E. Marx, Christine; Grant, Gerry; B. Stein, Murray; Qin, Xuejun; Jain, Sonia; W. McAllister, Thomas; Zafonte, Ross; J. Lang, Ariel; Coimbra, Raúl; Andaluz, Norberto; Shutter, Lori; S. George, Mark; Mid-Atlantic MIRECC Workgroup, VA; Brancu, Mira; S. Calhoun, Patrick; A. Dedert, Eric; B. Elbogen, Eric; A. Fairbank, John; A. Hurley, Robin; D. Kilts, Jason; C. Kirby, Angela; E. Marx, Christine; D. McDonald, Scott; D. Moore, Scott; A. Morey, Rajendra; C. Naylor, Jennifer; A. Rowland, Jared; Swinkels, Cindy; T. Szabo, Steven; H. Taber, Katherine; A. Tupler, Larry; E. Van Voorhees, Elizabeth; E. Yoash-Gantz, Ruth; PTSD Epigenetics Workgroup, PGC; Basu, Archana; A. Brick, Leslie; Dalvie, Shareefa; P. Daskalakis, Nikolaos; Ensink, Judith; Hemmings, Sian; J. Herringa, Ryan; Ikiyo, Sylvanus; Koen, Nastassja; Fen Kuan, Pei; L. Montalvo‐Ortiz, Janitza; Nispeling, Danny; R. Pfeiffer, John; Qin, Xuejun; J. Ressler, Kerry; Schijven, Dick; Seedat, Soraya; Shinozaki, Gen; A. Sumner, Jennifer; Swart, Patricia; R. Tyrka, Audrey; van Zuiden, Mirjam; H. Wani, Agaz; J. Wolf, Erika; S. Zannas, Anthony; Uddin, Monica; M. Nievergelt, Caroline

doi:10.1038/s41467-020-19615-x

Public

Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR

Published in Nature Communications • Nov 24, 2020

Authors:

Alicia K. Smith

Andrew Ratanatharathorn

Adam X. Maihofer

Abstract

Epigenetic differences may help to distinguish between PTSD cases and trauma-exposed controls. Here, we describe the results of the largest DNA methylation meta-analysis of PTSD to date. Ten cohorts, military and civilian, contribute blood-derived DNA methylation data from 1,896 PTSD cases and traum...

Subject

Epigenome

Methylation

DNA methylation

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!