Rapid Simultaneous Determination of 14 Antidepressants and 13 Antipsychotics in Human Plasma by Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry With Dynamic Multiple Reaction Monitoring and Its Application to Therapeutic Drug Monitoring.

H, Lyu; B, Chen; X, Xu; C, Zhu; C, Ma; Y, Du; F, Liu; C, Wu

doi:10.1097/ftd.0000000000000839

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Rapid Simultaneous Determination of 14 Antidepressants and 13 Antipsychotics in Human Plasma by Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry With Dynamic Multiple Reaction Monitoring and Its Application to Therapeutic Drug Monitoring.

Shared by NobleBlocks on Aug 1, 2021 • 12:00 AM UTC

Authors:

Lyu H

Chen B

Xu X

Abstract

Background A comprehensive, stable, and efficient high-performance liquid chromatography-tandem mass spectrometry method was developed for rapidly analyzing 14 antidepressants and 13 antipsychotics in human plasma for routine clinical therapeutic drug monitoring.Methods Simple protein precipitation ...

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