Anakinra usage in febrile infection related epilepsy syndrome: an international cohort.

Lai, Yi-Chen; Muscal, Eyal; Wells, Elizabeth; Shukla, Nikita; Eschbach, Krista; Hyeong Lee, Ki; Kaliakatsos, Marios; Desai, Nevedita; Wickström, Ronny; Viri, Maurizio; Freri, Elena; Granata, Tiziana; Nangia, Srishti; Dilena, Robertino; Brunklaus, Andreas; S Wainwright, Mark; P Gorman, Mark; M Stredny, Coral; Asiri, Abdurhman; Hundallah, Khalid; Doja, Asif; Payne, Eric; Wirrell, Elaine; Koh, Sookyong; L Carpenter, Jessica; Riviello, James

doi:10.1002/acn3.51229

Public

Anakinra usage in febrile infection related epilepsy syndrome: an international cohort.

Shared by NobleBlocks on Dec 1, 2020 • 12:00 AM UTC

Authors:

Yi-Chen Lai

Eyal Muscal

Elizabeth Wells

Abstract

Febrile-infection related epilepsy syndrome (FIRES) is a devastating neurological condition characterized by a febrile illness preceding new onset refractory status epilepticus (NORSE). Increasing evidence suggests innate immune dysfunction as a potential pathological mechanism. We report an interna...

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