Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain

Madore, C.; Leyrolle, Q.; Morel, L.; Rossitto, M.; D. Greenhalgh, A.; C. Delpech, J.; Martinat, M.; Bosch-Bouju, C.; Bourel, J.; Rani, B.; Lacabanne, C.; Thomazeau, A.; E. Hopperton, K.; Beccari, S.; Sere, A.; Aubert, A.; De Smedt-Peyrusse, V.; Lecours, C.; Bisht, K.; Fourgeaud, L.; Gregoire, S.; Bretillon, L.; Acar, N.; J. Grant, N.; Badaut, J.; Gressens, P.; Sierra, A.; Butovsky, O.; E. Tremblay, M.; P. Bazinet, R.; Joffre, C.; Nadjar, A.; Layé, S.

doi:10.1038/s41467-020-19861-z

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Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain

Shared by NobleBlocks on Nov 28, 2020 • 12:00 AM UTC

Authors:

C. Madore

Q. Leyrolle

L. Morel

Abstract

Abstract Omega-3 fatty acids (n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and developing countries is accompanied by a progressive reduction in dietary intake of n-3 PUFAs. Low maternal intake of n-3 PUFAs has been linked to...

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