Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Voysey, Merryn; Ann Costa Clemens, Sue; A Madhi, Shabir; Y Weckx, Lily; M Folegatti, Pedro; K Aley, Parvinder; Angus, Brian; L Baillie, Vicky; L Barnabas, Shaun; E Bhorat, Qasim; Bibi, Sagida; Briner, Carmen; Cicconi, Paola; M Collins, Andrea; Colin-Jones, Rachel; L Cutland, Clare; C Darton, Thomas; Dheda, Keertan; J A Duncan, Christopher; R W Emary, Katherine; J Ewer, Katie; Fairlie, Lee; N Faust, Saul; Feng, Shuo; M Ferreira, Daniela; Finn, Adam; L Goodman, Anna; M Green, Catherine; A Green, Christopher; T Heath, Paul; Hill, Catherine; Hill, Helen; Hirsch, Ian; H C Hodgson, Susanne; Izu, Alane; Jackson, Susan; Jenkin, Daniel; C D Joe, Carina; Kerridge, Simon; Koen, Anthonet; Kwatra, Gaurav; Lazarus, Rajeka; M Lawrie, Alison; Lelliott, Alice; Libri, Vincenzo; J Lillie, Patrick; Mallory, Raburn; V A Mendes, Ana; P Milan, Eveline; M Minassian, Angela; McGregor, Alastair; Morrison, Hazel; F Mujadidi, Yama; Nana, Anusha; J O’Reilly, Peter; D Padayachee, Sherman; Pittella, Ana; Plested, Emma; M Pollock, Katrina; N Ramasamy, Maheshi; Rhead, Sarah; V Schwarzbold, Alexandre; Singh, Nisha; Smith, Andrew; Song, Rinn; D Snape, Matthew; Sprinz, Eduardo; K Sutherland, Rebecca; Tarrant, Richard; C Thomson, Emma; Estée Török, M; Toshner, Mark; P J Turner, David; Vekemans, Johan; L Villafana, Tonya; E E Watson, Marion; J Williams, Christopher; D Douglas, Alexander; V S Hill, Adrian; Lambe, Teresa; C Gilbert, Sarah; J Pollard, Andrew; Aban, Marites; Abayomi, Fatola; Abeyskera, Kushala; Aboagye, Jeremy; Adam, Matthew; Adams, Kirsty; Adamson, James; A. Adelaja, Yemi; Adewetan, Gbadebo; Adlou, Syed; Ahmed, Khatija; Akhalwaya, Yasmeen; Akhalwaya, Saajida; Alcock, Andrew; Ali, Aabidah; R. Allen, Elizabeth; Allen, Lauren; C. D. S. C Almeida, Thamires; P.S. Alves, Mariana; Amorim, Fabio; Andritsou, Foteini; Anslow, Rachel; Appleby, Matthew; H. Arbe-Barnes, Edward; P. Ariaans, Mark; Arns, Beatriz; Arruda, Laiana; Azi, Paula; Azi, Lorena; Babbage, Gavin; Bailey, Catherine; F. Baker, Kenneth; Baker, Megan; Baker, Natalie; Baker, Philip; Baldwin, Lisa; Baleanu, Ioana; Bandeira, Danieli; Bara, Anna; A.S. Barbosa, Marcella; Barker, Debbie; D. Barlow, Gavin; Barnes, Eleanor; S. Barr, Andrew; R. Barrett, Jordan; Barrett, Jessica; Bates, Louise; Batten, Alexander; Beadon, Kirsten; Beales, Emily; Beckley, Rebecca; Belij-Rammerstorfer, Sandra; Bell, Jonathan; Bellamy, Duncan; Bellei, Nancy; Belton, Sue; Berg, Adam; Bermejo, Laura; Berrie, Eleanor; Berry, Lisa; Berzenyi, Daniella; Beveridge, Amy; R. Bewley, Kevin; Bexhell, Helen; Bhikha, Sutika; E. Bhorat, Asad; E. Bhorat, Zaheda; Bijker, Else; Birch, Geeta; Birch, Sarah; Bird, Adam; Bird, Olivia; Bisnauthsing, Karen; Bittaye, Mustapha; Blackstone, Katherine; Blackwell, Luke; Bletchly, Heather; L. Blundell, Caitlin; R. Blundell, Susannah; Bodalia, Pritesh; C. Boettger, Bruno; Bolam, Emma; Boland, Elena; Bormans, Daan; Borthwick, Nicola; Bowring, Francesca; Boyd, Amy; Bradley, Penny; Brenner, Tanja; Brown, Phillip; Brown, Claire; Brown-O'Sullivan, Charlie; Bruce, Scott; Brunt, Emily; Buchan, Ruaridh; Budd, William; A. Bulbulia, Yusuf; Bull, Melanie; Burbage, Jamie; Burhan, Hassan; Burn, Aileen; R. Buttigieg, Karen; Byard, Nicholas; Cabera Puig, Ingrid; Calderon, Gloria; Calvert, Anna; Camara, Susana; Cao, Michelangelo; Cappuccini, Federica; R. Cardoso, João; Carr, Melanie; W. Carroll, Miles; Carson-Stevens, Andrew; de M. Carvalho, Yasmin; A.M. Carvalho, José; R. Casey, Helen; Cashen, Paul; Castro, Thais

doi:10.1016/s0140-6736(20)32661-1

Public

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Shared by NobleBlocks on Jan 1, 2021 • 12:00 AM UTC

Authors:

Merryn Voysey

Sue Ann Costa Clemens

Shabir A Madhi

Research Assistant

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