IgA dominates the early neutralizing antibody response to SARS-CoV-2

Sterlin, Delphine; Mathian, Alexis; Miyara, Makoto; Mohr, Audrey; Anna, François; Claër, Laetitia; Quentric, Paul; Fadlallah, Jehane; Devilliers, Hervé; Ghillani, Pascale; Gunn, Cary; Hockett, Rick; Mudumba, Sasi; Guihot, Amélie; Luyt, Charles-Edouard; Mayaux, Julien; Beurton, Alexandra; Fourati, Salma; Bruel, Timothée; Schwartz, Olivier; Lacorte, Jean-Marc; Yssel, Hans; Parizot, Christophe; Dorgham, Karim; Charneau, Pierre; Amoura, Zahir; Gorochov, Guy

doi:10.1126/scitranslmed.abd2223

Public

IgA dominates the early neutralizing antibody response to SARS-CoV-2

Shared by NobleBlocks on Jan 20, 2021 • 12:00 AM UTC

Authors:

Delphine Sterlin

Alexis Mathian

Makoto Miyara

Abstract

Early specific antibody responses against SARS-CoV-2 include IgG, IgM, and IgA, but IgA may neutralize virus and control infection to a larger extent.

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