Trisomy 21–induced dysregulation of microglial homeostasis in Alzheimer’s brains is mediated by USP25

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Published in Science Advances • Jan 1, 2021

Authors:

Qiuyang Zheng

Guilin Li

Shihua Wang

Abstract

Trisomy 21 induces microglial dysregulation in the Alzheimer’s brain through the perturbation of the ubiquitin-proteasome system.

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