Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study

Štorkánová, Hana; Oreská, Sabína; Špiritović, Maja; Heřmánková, Barbora; Bubová, Kristýna; Komarc, Martin; Pavelka, Karel; Vencovský, Jiří; Distler, Jörg H W; Šenolt, Ladislav; Bečvář, Radim; Tomčík, Michal

doi:10.1038/s41598-020-79139-8

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Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study.

Published in Scientific reports • Jan 7, 2021

NobleIDNI2P35W01R29S85

Authors:

Hana Štorkánová

,

Sabína Oreská

,

Maja Špiritović

Abstract

Our previous study demonstrated increased expression of Heat shock protein (Hsp) 90 in the skin of patients with systemic sclerosis (SSc). We aimed to evaluate plasma Hsp90 in SSc and characterize its association with SSc-related features. Ninety-two SSc patients and 92 age-/sex-matched healthy cont...

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