Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults

Libster, Romina; Pérez Marc, Gonzalo; Wappner, Diego; Coviello, Silvina; Bianchi, Alejandra; Braem, Virginia; Esteban, Ignacio; T. Caballero, Mauricio; Wood, Cristian; Berrueta, Mabel; Rondan, Anibal; Lescano, Gabriela; Jordão Alcântara Cruz, Pablo; Ritou, Yvonne; Fernández Viña, Valeria; Álvarez Paggi, Damián; Esperante, Sebastián; Ferreti, Adrián; Ofman, Gastón; Ciganda, Álvaro; Rodríguez, Rocío; Lantos, Jorge; Valentini, Ricardo; Itcovici, Nicolás; Hintze, Alejandra; Laura Oyarvide, María; Etchegaray, Candela; Neira, Alejandra; Name, Ivonne; Alfonso, Julieta; López Castelo, Rocío; Caruso, Gisela; Rapelius, Sofía; Alvez, Fernando; Etchenique, Federico; Dimase, Federico; Alvarez, Darío; S. Aranda, Sofía; Sánchez Yanotti, Clara; De Luca, Julián; Jares Baglivo, Sofía; Laudanno, Sofía; Nowogrodzki, Florencia; Larrea, Ramiro; Dolores Silveyra, María; Leberzstein, Gabriel; Debonis, Alejandra; Molinos, Juan; Santiago Gonzalez, Miguel; García Pérez, Eduardo; Kreplak, Nicolás; Pastor Argüello, Susana; Gibbons, Luz; Althabe, Fernando; Bergel, Eduardo; P. Polack, Fernando

doi:10.1056/nejmoa2033700

Public

Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults

Published in New England Journal of Medicine • Jan 6, 2021

Authors:

Romina Libster

Gonzalo Pérez Marc

Diego Wappner

Abstract

BACKGROUND: Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered earlier in the course of illness. METHODS: We...

Subject

Coronavirus disease 2019 (COVID-19)

Convalescent plasma

2019-20 coronavirus outbreak

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