STIM1 promotes angiogenesis by reducing exosomal miR-145 in breast cancer MDA-MB-231 cells

Pan, Shunli; Zhao, Xiaoxia; Shao, Chen; Fu, Bingjie; Huang, Yingying; Zhang, Ning; Dou, Xiaojing; Zhang, Zhe; Qiu, Yuling; Wang, Ran; Jin, Meihua; Kong, Dexin

doi:10.1038/s41419-020-03304-0

Public

STIM1 promotes angiogenesis by reducing exosomal miR-145 in breast cancer MDA-MB-231 cells

Published in Cell Death and Disease • Jan 4, 2021

Authors:

Shunli Pan

Xiaoxia Zhao

Chen Shao

Abstract

signals. MicroRNAs (miRNAs) have been reported to be potential therapeutic targets for many diseases, including breast cancer. Recently, we investigated the effect of exosomes from STIM1-knockout breast cancer MDA-MB-231 cells (Exo-STIM1-KO), and from SKF96365-treated MDA-MB-231 cells (Exo-SKF) on a...

Subject

Angiogenesis

Cancer research

Breast cancer

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