Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020

Leung, Kathy; HH Shum, Marcus; Leung, GM; Tsan‐Yuk Lam, Tommy; T. Wu, Joseph

doi:10.2807/1560-7917.es.2020.26.1.2002106

Public

Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020

Published in Eurosurveillance • Jan 7, 2021

Authors:

Kathy Leung

Marcus HH Shum

GM Leung

Abstract

Two new SARS-CoV-2 lineages with the N501Y mutation in the receptor-binding domain of the spike protein spread rapidly in the United Kingdom. We estimated that the earlier 501Y lineage without amino acid deletion Δ69/Δ70, circulating mainly between early September and mid-November, was 10% (6-13%) m...

Subject

Lineage (genetic)

Transmissibility (structural dynamics)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

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