Umbilical cord mesenchymal stem cells for COVID-19 acute respiratory distress syndrome: A double-blind, phase 1/2a, randomized controlled trial

Lanzoni, Giacomo; Linetsky, Elina; Correa, Diego; Messinger, Shari; A. Alvarez, Roger; Kouroupis, Dimitrios; Alvarez Gil, Ana; Poggioli, Raffaella; Ruiz, Phillip; Marttos, Antonio; Hirani, Khemraj; A. Bell, Crystal; Kusack, Halina; Rafkin, Lisa; A. Baidal, David; Pastewski, Andrew; Gawri, Kunal; Leñero, Clarissa; Mantero, Alejandro; Wishnek Metalonis, Sarah; Wang, Xiaojing; Roque, Luis; Masters, Burlett; S. Kenyon, Norma; Ginzburg, Enrique; Xu, Xiumin; Jen Tan, Ming; I. Caplan, Arnold; K. Glassberg, Marilyn; Alejandro, Rodolfo; Ricordi, Camillo

doi:10.1002/sctm.20-0472

Public

Umbilical cord mesenchymal stem cells for COVID-19 acute respiratory distress syndrome: A double-blind, phase 1/2a, randomized controlled trial

Published in Stem Cells Translational Medicine • Jan 5, 2021

Authors:

Giacomo Lanzoni

Elina Linetsky

Diego Correa

Abstract

Abstract Acute respiratory distress syndrome (ARDS) in COVID-19 is associated with high mortality. Mesenchymal stem cells are known to exert immunomodulatory and anti-inflammatory effects and could yield beneficial effects in COVID-19 ARDS. The objective of this study was to determine safety and exp...

Subject

Umbilical cord

Mesenchymal stem cell

Medicine

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