Metabolic Profile of Four Selected Cathinones in Microsome Incubations: Identification of Phase I and II Metabolites by Liquid Chromatography High Resolution Mass Spectrometry

Lopes, Beatriz; João Caldeira, Maria; Gaspar, Helena; M. M. Antunes, Alexandra

doi:10.3389/fchem.2020.609251

Public

Metabolic Profile of Four Selected Cathinones in Microsome Incubations: Identification of Phase I and II Metabolites by Liquid Chromatography High Resolution Mass Spectrometry

Published in Frontiers in Chemistry • Jan 12, 2021

Authors:

Beatriz Lopes

Maria João Caldeira

Helena Gaspar

Abstract

Consumption of synthetic cathinones, the second largest class of new psychoactive substances (NPS) reported worldwide, represents a serious public health risk. One of the biggest challenges created by the rapid spread of NPS on the illegal drug market is the discovery of selective biomarkers for the...

Subject

Chromatography

Chemistry

Mass spectrometry

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