Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69–V70, France, August to December 2020

Bal, Antonin; Destras, Grégory; Gaymard, Alexandre; Stéfic, Karl; Marlet, Julien; Eymieux, Sébastien; Regue, Hadrien; Semanas, Quentin; d’Aubarede, Constance; Billaud, Geneviève; Laurent, Frédéric; González, Claudia; Mekki, Yahia; Valette, Martine; Bouscambert, Maude; Gaudy‐Graffin, Catherine; Lina, Bruno; Morfin, Florence; Josset, Laurence; COVID-Diagnosis HCL Study Group, the

doi:10.2807/1560-7917.es.2021.26.3.2100008

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Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69–V70, France, August to December 2020

Published in Eurosurveillance • Jan 21, 2021

Authors:

Antonin Bal

Grégory Destras

Alexandre Gaymard

Abstract

We report the strategy leading to the first detection of variant of concern 202012/01 (VOC) in France (21 December 2020). First, the spike (S) deletion H69-V70 (ΔH69/ΔV70), identified in certain SARS-CoV-2 variants including VOC, is screened for. This deletion is associated with a S-gene target fail...

Subject

Spike (software development)

Identification (biology)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

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