5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition

Sethy, Chinmayee; Nath Kundu, Chanakya

doi:10.1016/j.biopha.2021.111285

Public

5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition

Published in Biomedicine & Pharmacotherapy • Jan 20, 2021

Authors:

Chinmayee Sethy

Chanakya Nath Kundu

Abstract

5-Fluorouracil (5-FU) has been an important anti-cancer drug to date. With an increase in the knowledge of its mechanism of action, various treatment modalities have been developed over the past few decades to increase its anti-cancer activity. But drug resistance has greatly affected the clinical u...

Subject

Metastasis

Fluorouracil

Cancer research

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