Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19

D. Lópes, Renato; Vieira Scarlatelli Macedo, Ariane; Gabriel Melo de Barros e Silva, Pedro; Moll‐Bernardes, Renata; M. dos Santos, Tiago; Mazza, Lilian; Feldman, André; Arruda, Guilherme; Campos de Albuquerque, Denílson; Camiletti, Angelina; Silvestre de Sousa, Andréa; Ceccatto de Paula, Thiago; G. D. Giusti, Karla; Domiciano, Rafael; Noya-Rabelo, Márcia; M. Hamilton, Alan; Alves Loures, Vitor; M. Dionísio, Rodrigo; Antônio Biagioni Furquim, Thyago; Augusto de Luca, Fábio; Bruno dos Santos Sousa, Ítalo; Santana Bandeira, Bruno; Zukowski, Cleverson; Oliveira, Ricardo; Barros Ribeiro, Noara; L. de Moraes, Jeffer; Luiz Fernandes Petriz, João; M. Pimentel, Adriana; S. Miranda, Jacqueline; Abufaiad, Barbara; Michael Gibson, C.; B. Granger, Christopher; H. Alexander, John; Ferreira de Souza, Olga; CORONA Investigators, BRACE

doi:10.1001/jama.2020.25864

Public

Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19

Published in JAMA • Jan 19, 2021

Authors:

Renato D. Lópes

Ariane Vieira Scarlatelli Macedo

Pedro Gabriel Melo de Barros e Silva

Abstract

Importance: It is unknown whether angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) have a positive, neutral, or negative effect on clinical outcomes in patients with coronavirus disease 2019 (COVID-19). Objective: To determine whether discontinuation compar...

Subject

Medicine

Interquartile range

Discontinuation

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