Focal Boost to the Intraprostatic Tumor in External Beam Radiotherapy for Patients With Localized Prostate Cancer: Results From the FLAME Randomized Phase III Trial

G. W. Kerkmeijer, Linda; H. Groen, Veerle; J. Pos, Floris; Haustermans, Karin; M. Monninkhof, Evelyn; Jan Smeenk, Robert; Kunze-Busch, Martina; C. J. de Boer, Johannes; van der Voort van Zijp, Jochem; van Vulpen, Marco; Draulans, Cédric; van den Bergh, Laura; Isebaert, Sofie; A. van der Heide, Uulke

doi:10.1200/jco.20.02873

Public

Focal Boost to the Intraprostatic Tumor in External Beam Radiotherapy for Patients With Localized Prostate Cancer: Results From the FLAME Randomized Phase III Trial

Shared by NobleBlocks on Mar 1, 2021 • 12:00 AM UTC

Authors:

Linda G. W. Kerkmeijer

Veerle H. Groen

Floris J. Pos

Abstract

PURPOSE This study investigates whether focal boosting of the macroscopic visible tumor with external beam radiotherapy increases biochemical disease-free survival (bDFS) in patients with localized prostate cancer. PATIENTS AND METHODS In the phase III, multicenter, randomized controlled Focal Lesio...

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