Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

Davar, Diwakar; Dzutsev, Amiran; A. McCulloch, John; R. Rodrigues, Richard; Chauvin, Joë-Marc; M. Morrison, Robert; DeBlasio, Richelle; Menna, Carmine; Ding, Quanquan; Pagliano, Ornella; Zidi, Bochra; Zhang, Shuowen; H. Badger, Jonathan; Vétizou, Marie; M. Cole, Alicia; R. Fernandes, Miriam; Prescott, Stephanie; Costa, Raquel; K. Balaji, Ascharya; Morgun, Andrey; Vujkovic-Cvijin, Ivan; Wang, Hong; A. Borhani, Amir; Schwartz, Marc; M. Dubner, Howard; Ernst, S.; Rose, Amy; G. Najjar, Yana; Belkaid, Yasmine; M. Kirkwood, John; Trinchieri, Giorgio; M. Zarour, Hassane

doi:10.1126/science.abf3363

Public

Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

Published in Science • Feb 4, 2021

Authors:

Diwakar Davar

Amiran Dzutsev

John A. McCulloch

Abstract

New fecal microbiota for cancer patients The composition of the gut microbiome influences the response of cancer patients to immunotherapies. Baruch et al. and Davar et al. report first-in-human clinical trials to test whether fecal microbiota transplantation (FMT) can affect how metastatic melanoma...

Subject

Fecal bacteriotherapy

Feces

Resistance (ecology)

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!