Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children

Ouldali, Naïm; Toubiana, Julie; Antona, Denise; Javouhey, Étienne; Madhi, Fouad; Lorrot, Mathie; Léger, Pierre-Louis; Galeotti, Caroline; Claude, Caroline; Wiedemann, Arnaud; Lachaume, Noémie; Ovaert, Caroline; Dumortier, Morgane; Kahn, Jean‐Emmanuel; Mandelcwajg, Alexis; Percheron, Lucas; Biot, Blandine; Bordet, Jeanne; Girardin, Marie‐Laure; Dawei Yang, David; Grimaud, Marion; Oualha, Mehdi; Allali, Slimane; Bajolle, Fanny; Beyler, Constance; Meinzer, Ulrich; Levy, Michaël; Paulet, Ana-Maria; Levy, Corinne; Cohen, Robert; Bélot, Alexandre; Angoulvant, François; Rames, Cinthia; Donzeau, A.; Léty, Sophie; Fedorczuk, Cristian; Lajus, Marion; Bensaïd, Philippe; Laoudi, Yacine; Pons, Charlotte; Beaucourt, Camille; de Pontual, Loïc; Aupiais, Camille; Lefèvre‐Utile, Alain; Richard, Muriel; Goisque, Etienne; Iriart, Xavier; Brissaud, Olivier; Bailhache, Marion; Segretin, Pierre; Molimard, Julie; Orcel, Marie-Clothilde; Benoist, Grégoire; Amouyal, Elsa; Guerder, Margaux; Pouyau, Robin; De Guillebon De Resnes, Jean-Marie; Mezgueldi, Ellia; Cour‐Andlauer, Fleur; Horvat, Côme; Poinsot, Pierre; Frachette, Cécile; Ouziel, Antoine; Gillet, Yves; Barrey, Catherine; Brouard, Jacques; Faucon, Caroline; Giniès, Henri; Ro, Vathanaksambath; Elanga, Narcisse; Gajdos, Vincent; Basmaci, Romain; Danékova, Névéna; Mutar, Hadile; Rouget, Sébastien; Torterüe, Xavier; Nattes, Elodie; Hau, Isabelle; Biscardi, Sandra; El Jurdi, Houmam; Jung, Camille; Epaud, Ralph; Delestrain, Céline; Carlier‐Gonod, Adèle; Chavy, Camille; Colomb, Benoît; Litzler-Renault, Stéphanie; S. Semama, Denis; Huet, Frédéric; Sarakbi, Mayssa; Mortamet, Guillaume; Bost-Bru, C.; Kevorkian‐Verguet, Charlotte; Lachaud, Matthias; Vinit, Caroline; Hentgen, Véronique; Leroux, Pascal; Bertrand, Valérie; Parrod, Caroline; Craiu, Irina; Kone-Paut, Isabelle; Durand, Philippe; Tissiere, Pierre; Morin, Luc; Miatello, Jordi; Morelle, Guillaume; Guiddir, Tamazoust; Borocco, Charlotte; Guillot, Camille; Leteurtre, Stéphane; Dubos, François; Jouancastay, Mylene; Recher, Morgan; Martinot, A.; Voeusler, Valentine; Languepin, Jeanne; Morand, Aurélie; Bosdure, E.; Bresson, Violaine; Vanel, Noémie; Ughetto, Fabrice; Michel, Fabrice; Marie, Caujolle; Blondé, Renaud; Nguyen, Jacqueline; Garrec, Nathalie; Chalvon-Demersay, A; Masserot‐Lureau, Caroline; Colas, Anne-Sophie; Ferrua, Claire; Larakeb, Anis; Benkaddouss, Sakina; Mathivon, Laurence; Monfort, Marie; Naji, Sanaa; Carbasse, Aurélia; Milési, Christophe; Schweitzer, Cyril; Giroux, Nathan; Boussard, Noël; Romefort, Bénédicte; Launay, É.; Gras‐Le Guen, Christèle; Ali, Ahmed; Blot, Nathalie; Tran, Antoine; Rancurel, Anne; Haas, H.; Afanetti, Mickael; Bernardor, Julie; Talmud, Déborah; Jhaouat, Imen; Monceaux, Françoise; Chosidow, Anaïs; Romain, Anne‐Sophie; Grimprel, E.; Rambaud, Jérôme; Jean, Sandrine; Starck, Julie; Levy, Corinne; Guedj, Romain; Carbajal, Ricardo; Parisot, Pauline; Poncelet, Géraldine; Wolff, Richard; Lacarra, Boris; Maroni, A.; Naudin, J.; Geslin, Guillaume; Maurice, Laure; Dehò, Anna; Lebourgeois, Fleur; Chomton, Marilyne; Dauger, Stéphane; Genuini, Mathieu; Benzouid, Chérine; Lokmer, Johanna; Bonnefoy, R.; Melki, Isabelle; Dingulu, Glory; Gaschignard, Jean; Ducrocq, Camille; Pouletty, Marie; Corseri, Olivier; Faye, Albert; Rybak, Alexis; Titomanlio, Luigi; Hurtaux, Marie-Françoise; Garcelain, Guislaine; Bonacorsi, Stéphane; Bidet, Philippe; Birgy, André; Renolleau, Sylvain; Lesage, Fabrice; Moulin, Florence; Dupic, Laurent; de Saint Blanquat, L.; Heilbronner, Claire; Vedrenne‐Cloquet, Meryl; Salvador, Elodie; Bendavid, Matthieu; de Marcellus, Charles; Chareyre, Judith; Pinhas, Yael; Brisse, J; Taylor, Mélissa; Debray, Agathe; Adnot, Pauline; Chalumeau, Martin; Abadie, Véronique; Frange, Pierre; F. Cohen, Jérémie; M. Curtis, William; Chappuy, Hélène; Belhadjer, Zahra; Auriau, Johanne; Méot, Mathilde; Houyel, Lucile; Bonnet, Damien; Delacourt, Christophe; Drummond, David; Bader‐Meunier, Brigitte; Quartier, Pierre; Delion, Fréderique; Blanc, Philippe; Caron, Elisabeth; Maledon, Natacha; Robert, Blandine; Pantalone, Létitia; Kouider, Hanane; Loeile, Camille; Loron, Gauthier; Vittot, Cécile; Blanc, Thierry; Pinquier, Didier; Buisson, F.; Flodrops, Hugues; Karim, Jamal-Bey; Sarton, Raphaëlle; Mokraoui, Fadhila; Escoda, Simon; Deschamps, Nina; Bonnemains, Laurent; Mahi, Sarah-Louisa; Mertes, Clara; Terzic, Joëlle; Idier, Charlotte; Benezech, Ariane; Simon, Thomas; Decramer, Stéphane; Karsenty, Clément; Bréhin, Camille; Chenichene, Soraya; Ursulescu, Nicoleta; Manteau, Céline; Delattre, Marie; Dalichoux, Bérengère

doi:10.1001/jama.2021.0694

Public

Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children

Published in JAMA • Feb 2, 2021

Authors:

Naïm Ouldali

Julie Toubiana

Denise Antona

Abstract

Importance: Multisystem inflammatory syndrome in children (MIS-C) is the most severe pediatric disease associated with severe acute respiratory syndrome coronavirus 2 infection, potentially life-threatening, but the optimal therapeutic strategy remains unknown. Objective: To compare intravenous immu...

Subject

Medicine

Methylprednisolone

Pediatrics

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