Once-Weekly Semaglutide in Adults with Overweight or Obesity

Wilding, John; L. Batterham, Rachel; Calanna, Salvatore; J. Davies, Melanie; F. Van Gaal, Luc; Lingvay, Ildiko; McGowan, Barbara; Rosenstock, Julio; Thi Dao Tran, Marie; A. Wadden, Thomas; Wharton, Sean; Yokote, Koutaro; Zeuthen, Niels; F. Kushner, Robert

doi:10.1056/nejmoa2032183

Public

Once-Weekly Semaglutide in Adults with Overweight or Obesity

Published in New England Journal of Medicine • Feb 10, 2021

Authors:

John Wilding

Rachel L. Batterham

Salvatore Calanna

Abstract

BACKGROUND: Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle intervention has not been confirmed. METHODS: In this double-blind trial, we enrolled 1961 ...

Subject

Semaglutide

Obesity

Overweight

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